8th WCIRDC PROGRAM OBJECTIVES
The program is designed to evaluate both clinical and basic science aspects of insulin resistance and hyperinsulinemia, as related either to overall pathophysiology and/or to key metabolic centers such as the beta cell, adipocyte, gut, and brain. Clinical topics may include any aspect of insulin resistance and its relationship to the causation and/or natural history of obesity, diabetes, hypertension, cardiovascular disease, dyslipidemia, PCOS, gestational diabetes, other endocrine abnormalities, inflammation, endothelial and vascular dysfunction, liver disease (NAFLD), malignancy, sleep apnea and sleep disorders in childhood, adolescence and adulthood. The interests of the congress include multi-hormonal aspects of obesity, incretin and other gut hormonal contributions to energy balance, and circadian rhythm as it relates to these metabolic mechanisms. Ultimately all these topics relate to improve the ability of the clinician to provide best care to the person with metabolic conditions like obesity, diabetes, dyslipidemia, hypertension and cardiovascular disease. Upon completion of this meeting, participants should be able to:
• Explain the role of insulin resistance (IR) and hyerinsulinemia in in CVD, liver disease, PCOS, CHF, and the development of certain cancers.
• Appreciate the impact of the world wide obesity, metabolic CV risks & diabetes epidemics in children and special populations.
• Recognize that insulin resistance may identify (obese) people who are at risk of developing metabolic disorders.
• Discuss the relationship between incretin, bile acid, gut hormones to the brain in the management of energy expenditure & storage
• Understand the comprehensive approach to the treatment of obesity, hypertension, dyslipidemia and prevention of cardiovascular disease.
• Describe the unique role of incretin and gut hormones in metabolic systems and energy balance and and their potential for reducing cardiovascular mobidity.
• Describe the relationship of IR to obesity and the fat cell.
• Relate the potential relationship of IR to circadian rhythm, sleep disorders, the brain, incretin hormones and metabolic disorders.
• Diagnose persons at a higher risk for developing diabetes, CVD and other metabolic disorders.
• Understand potential therapeutic modalities and their complexities in the treatment of these metabolic disorders.
